GLP-1 Receptor

기타 GPCR & G Protein 억제제

Hedgehog/Smoothened PKA CGRP Receptor Endothelin Receptor S1P Receptor Cannabinoid Receptor SGLT Opioid Receptor GPR CCR

Cat.No.	제품명	정보	제품 사용 인용
S9851	Danuglipron (PF-06882961)	Danuglipron (PF-06882961) is a non-peptide agonist that activates the canonical G protein signaling activity only in the Glucagon-like peptide-1 (GLP-1) receptor with Trp33^ECD.
S8256	Liraglutide	Liraglutide is a long-acting glucagon-like peptide-1(GLP-1) receptor agonist.	Frontiers in Endocrinology, June 25, 2024, 1395028 bioRxiv, December 17, 2024, nan Diabetes, December 1, 2025, 2375-2389
P1273^New	Ecnoglutide（XW003）	Ecnoglutide (XW003) is a long‑acting, cAMP‑biased agonist of the glucagon‑like peptide‑1 (GLP‑1) receptor that selectively enhances cAMP signaling over β‑arrestin recruitment, and exhibits potential for the treatment of type 2 diabetes and obesity.
E1827	AZD5004 (ECC5004)	ECC5004(AZD5004, GLP-1 agonist (Eccogene)) is a small molecule GLP-1 receptor agonist (GLP-1RA) used to treat digestive system diseases and endocrine and metabolic diseases. ECC5004 has the potential to be used to treat obesity, type 2 diabetes and metabolic dysfunction-associated steatohepatitis (MASH) disease.
P1230	Retatrutide (LY3437943)	Retatrutide (LY3437943) acts as a triple agonist peptide of the glucagon receptor (GCGR), glucagon-like peptide-1 receptor (GLP-1R) and glucosedependent insulinotropic polypeptide receptor (GIPR). Retatrutide binds to human GCGR, GLP-1R, and GIPR with EC50 values of 5.79, 0.775 nM, and 0.0643, respectively. Retatrutide has the potential for use in research on obesity.