Home GPCR & G Protein -Neuronal Signaling Cannabinoid Receptor CB1-Sélectif Agonists | Antagonists

CB1-Sélectif Agonists | Antagonists

  • CB1
  • CB2
N° de cat. Nom du produit Informations Sélectif / Pan IC50 / Ki
S8012 Otenabant (CP-945598) HCl Otenabant (CP-945598) HCl is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor. Phase 1. Selective rCB1, Ki: 2.8 nM; hCB1, Ki: 0.7 nM
S3021 Rimonabant Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Selective hCB1, IC50: 13.6 nM
S2819 AM251 AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 receptors in brain. Selective
S1534 Org 27569 Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity. Selective
S1544 AM1241 AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor. Pan CB1, Ki: 280 nM