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PKCζ Inhibitors

N° de cat.	Nom du produit	Informations	Sélectif / Pan	IC50 / Ki
S2911	Go 6983	Go 6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ and PKCδ with IC50 of 7 nM, 7 nM, 6 nM and 10 nM, respectively; less potent to PKCζ and inactive to PKCμ.	Pan	PKCζ, IC50: 60 nM
S1421	Staurosporine	Staurosporine is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM). Phase 3.	Pan	PKCζ, IC50: 1086 nM