클론 번호:B8.2C12
Anti-mouse TIM-3 (CD366)-InVivo monoclonal antibody reacts with mouse TIM-3 (T cell immunoglobulin and mucin domain-3) also known as CD366. TIM-3 is specifically expressed at high levels on the surface of Th1 lymphocytes. This B8.2C12 antibody binds to the BALB/c allele of TIM-3 while reactivity to the C57Bl/6 allele. Inhibition of TIM-3 signaling in mice exacerbates experimental autoimmune encephalomyelitis and promotes IFNγ production and Th1 cell proliferation.
| 분자량 | 150 kDa |
|---|---|
| 클론 | B8.2C12 |
| 아이소타입 | Rat IgG2a, κ |
| 적용 | Anti-mouse TIM-3 (CD366)-InVivo |
| 출처 | CHO |
| 정제 | Protein G |
| 멸균 | 0.2 μM filtered |
| 제형 | PBS, pH 7.0 Contains no stabilizers or preservatives |
| 보관 | Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
*이 타겟에 대해 시판되는 다양한 클론 제품에 대한 문헌 분석 결과, Selleck이 선정한 클론이 더 자주 활용되는 것으로 나타났습니다. (2024년 9월까지의 데이터)