Home화합물 라이브러리Fragment Library

Fragment Library

카탈로그 번호L1600

Fragment-Based Drug Discovery (FBDD)를 위한 1015개의 Fragment 화합물로 구성된 고유한 컬렉션입니다.

96 well plates

라이브러리 맞춤 설정:

인용: 3 출판물

Fragment Library 목차

설명 및 장점

• A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD)
 
• FBDD has emerged as an alternative approach for high-throughput screening (HTS) in discovering drug
 
• These fragments with low molecular weight are extremely suitable for screening clinical candidates with good drug-like properties,and more and more compounds discovered by FBDD are entering the clinic
 
• FBDD can save research cost and make it easier to screen high-performance drugs
  Range Average
MolWeight 92 to 291 164.8
LogP <3.8 1.5
Num_H_Acceptors 0 to 6 2.4
Num_H_Donors 0 to 3 1
Num_RotatableBonds 0 to 8 1.5
PSA 0 to 99 8

 

제품 세부 정보

제형 1015 compounds pre-dissolved in 10mM DMSO
용기 알루미늄 호일로 밀봉된 96 딥 웰 플레이트
안정성 12 months -20°C in DMSO
24 months -80°C in DMSO
배송 아이스팩 또는 드라이아이스

Selleck 화합물 라이브러리를 사용한 사례 연구

Fragment Library 구성

HTS 시설 파트너

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania