Home화합물 라이브러리Protein-protein Interaction Inhibitor Library

Protein-protein Interaction Inhibitor Library

카탈로그 번호L8100

고처리량 스크리닝(HTS) 및 고함량 스크리닝(HCS)에 사용되는 407가지 단백질-단백질 상호작용(PPI) 억제제 고유 컬렉션입니다.

96 well plates

라이브러리 맞춤 설정:

인용: 321 출판물

Protein-protein Interaction Inhibitor Library 목차

설명 및 장점

•Protein-protein interactions (PPI) represent a vast class of therapeutic targets both inside and outside the cell.Inhibitors of a number of protein–protein interactions (PPIs) have emerged as potential anticancer drug candidates; 
 
•A unique collection of 407 protein-protein Interaction(PPI) Inhibitors used for high throughput screening(HTS) and high content screening(HCS);
 
•Targets PD-1/PD-L1, BCL family, Bromodomains, MDM2, HIV integrase, etc.  
 
•Some compounds have been approved by the FDA;
 
•Structurally diverse,medicinally active,and cell permeable;
 
•Rich documentation with structure and bioactivity information;
 
•NMR and HPLC validated to ensure high purity.       

제품 세부 정보

제형 384 compounds pre-dissolved in 10mM DMSO, 12 compounds pre-dissolved in 10mM water, 9 compounds pre-dissolved in 2mM DMSO and 2 compounds pre-dissolved in 2mM water
용기 알루미늄 호일로 밀봉된 96 딥 웰 플레이트
안정성 12 months -20°C in DMSO
24 months -80°C in DMSO
배송 아이스팩 또는 드라이아이스

Selleck 화합물 라이브러리를 사용한 사례 연구

Protein-protein Interaction Inhibitor Library 구성

HTS 시설 파트너

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania