Highly Selective Inhibitor Library

카탈로그 번호L3500

123개 이상의 표적을 포함하는 590개의 검증된 고도로 선택적인 억제제들의 고유한 컬렉션.

라이브러리 맞춤 설정:

인용: 337 출판물

• A unique collection of 590 validated highly selective inhibitors with covering over 123 targets

• Selectivity is at least 100-fold higher relative to non-primary target(s)

• Each compound was selected based on its ability to principally interact with a single target, leading to minimal off-target activity

•Targets cover a wide variety of signaling pathways, including PI3K/Akt, MAPK, PTK, JAK, apoptosis, and others!

• This unique tool is ideal for studying mechanisms of action or for target screening

• Compounds are structurally diverse, biologically active, and cell permeable

• Selleck provides rich supporting documentation which includes compound structure and customer reviews

• Compounds are NMR and HPLC validated to ensure our customers receive high purity compounds

제형	555 compounds pre-dissolved in 10mM DMSO, 9 compounds pre-dissolved in 10mM water and 26 compounds pre-dissolved in 2mM DMSO
용기	알루미늄 호일로 밀봉된 96 딥 웰 플레이트
안정성	12 months	-20°C	in DMSO
안정성	24 months	-80°C	in DMSO
배송	아이스팩 또는 드라이아이스

간암에 대한 GPCR Compound Library 적용 (이 논문은 Nature에 게재되었습니다 (IF

Nature.2019;574(7777):268-272
결장직장암에 대한 Kinase Inhibitor Library 적용 (이 논문은 Nature Communications에 게재되었습니다 (IF

Nat Commun. 2019 16;10(1):2197
항바이러스에 대한 FDA-approved Drug Library 적용 (이 논문은 Cell Research에 게재되었습니다 (IF

Cell Res. 2019;29(9):739-753
대사에 대한 FDA-approved Drug Library 적용 (이 논문은 Movement Disorders에 게재되었습니다 (IF

Mov Disord. 2019;34(3):323-334
급성 림프모구성 백혈병에 대한 Epigenetics Compound Library 적용 (이 논문은 Blood에 게재되었습니다 (IF

Blood. 2019 17;134(16):1323-1336
종양 면역학에 대한 Inhibitor Library 적용 (이 논문은 Cancer Immunol Res에 게재되었습니다 (IF

Cancer Immunol Res.2017;5(9):790-803