TGF-beta/Smad compound library

카탈로그 번호L5600

TGF-베타/Smad 경로 연구에 사용되는 생물학적 활성을 가진 155가지 저분자 화합물의 고유한 컬렉션입니다.

96 well plates

라이브러리 맞춤 설정:

인용: 323 출판물

설명 및 장점

• A unique collection of 155 small molecule compounds for high throughput screening(HTS) and high content screening (HCS).
 
• Target includes TGF-beta/SmadTGF-β Receptor, PKC, ROCK and RAS
 
• A useful tool for finding tumor therapeutic mechanism and  new targets.
 
• For studying human diseases, exploring the pathogenesis of diseases such as cancer, and opening noval therapeutic ways. 
 
• Structurally diverse, medicinally active, and cell permeable.
 
• Rich documentation with structure description, target information, IC50 values and customer reviews.
 
• NMR and HPLC validated to ensure high purity.

 

제품 세부 정보

제형 149 compounds pre-dissolved in 10mM DMSO, 2 compounds pre-dissolved in 10mM water and 4 compounds pre-dissolved in 2mM DMSO
용기 알루미늄 호일로 밀봉된 96 딥 웰 플레이트
안정성 12 months -20°C in DMSO
24 months -80°C in DMSO
배송 아이스팩 또는 드라이아이스

Selleck 화합물 라이브러리를 사용한 사례 연구

TGF-beta/Smad compound library 구성

HTS 시설 파트너

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania