Home Neuronal Signaling -GPCR & G Protein 5-HT Receptor 5-HT7-선택적 Antagonists

5-HT7-선택적 Antagonists

  • 5-HT1
  • 5-HT2
  • 5-HT3
  • 5-HT4
  • 5-HT6
  • 5-HT7
  • 5-HT5
Cat.No. 제품명 정보 선택적 / 팬 IC50 / Ki
S2849 SB269970 HCl SB269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3, exhibits >50-fold selectivity against other receptors. Selective 5-HT7, pKi: 8.3
S1283 Asenapine Asenapine is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder. Pan 5-HT7, pKi: 9.94
S1615 Risperidone Risperidone is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder. Pan 5-HT7, Ki: 6.6 nM
S2677 BRL-15572 BRL-15572 is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor. Pan 5-HT7, pKi: 6.3