Home DNA Damage/DNA Repair Topoisomerase Topo IV-선택적 Inhibitors

Topo IV-선택적 Inhibitors

  • Topo I
  • Topo II
  • Topo IV
Cat.No. 제품명 정보 선택적 / 팬 IC50 / Ki
S2027 Ciprofloxacin Ciprofloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity, with MIC90 of 0.024-6 μM. Selective
S1463 Ofloxacin Ofloxacin is a synthetic broad-spectrum antimicrobial agent. Pan
S1464 Marbofloxacin Marbofloxacin is a potent antibiotic inhibiting bacterial DNA replication. Pan
S2328 Nalidixic acid Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase. Pan
S2492 Novobiocin Sodium Novobiocin Sodium is a very potent bacterial DNA gyrase and human organic anion transporters with Ki of 14.87 ± 0.40 μM for hOAT1, 4.77 ± 1.12 μM for hOAT3 and 90.50 ± 7.50 μM for hOAT4. Pan
S1465 Moxifloxacin HCl Moxifloxacin is a fourth-generation synthetic fluoroquinolone antibacterial agent. Pan
S4006 Clinafloxacin Clinafloxacin is a fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumoniae. Pan
S1940 Levofloxacin Levofloxacin is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections. Pan
S1509 Norfloxacin Norfloxacin is a broad-spectrum antibiotic. Pan
S1756 Enoxacin Enoxacin is an oral broad-spectrum fluoroquinolone antibacterial agent used in the treatment of urinary tract infections and gonorrhea. Insomnia is a common adverse effect. Pan
S1340 Gatifloxacin Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, and inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Pan