Home Cytoskeletal Signaling HSP 조절제 Elesclomol (STA-4783)

연구용

Elesclomol (STA-4783) Cuproptosis 유도제

제품 번호: S1052

Elesclomol (STA-4783)은 종양 세포에서 Apoptosis related 사건을 유도하는 강력한 산화 스트레스 유발제입니다. 임상 3상. Elesclomol은 FDX1 α2/α3 나선 및 β5 가닥에 특이적으로 결합하여 FDX1 매개 Fe-S 클러스터 생합성을 억제합니다. Elesclomol (STA-4783)은 강력한 구리 이온ophore이며 구리 의존성 세포 사멸(Cuproptosis) 연구에 사용될 수 있습니다.
Elesclomol (STA-4783) HSP 조절제 Chemical Structure

화학 구조

분자량: 400.5

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품질 관리 (Quality Control)

배치: 순도: 99.60%
99.60

함께 자주 사용되는 제품 Elesclomol (STA-4783)

Genipin

It and Genipin significantly reduce mitochondrial membrane potential and induce apoptosis in A549 cells.

세포 배양, 처리 및 작업 농도
(Cell Culture, Treatment & Working Concentration)

세포주 분석 유형 농도 배양 시간 제형 활성 설명 PMID
PC3 cells Function assay Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISA, IC50=0.113 μM 21341675
F-36P cells Proliferation assay Antiproliferative activity against human F-36P cells, IC50=0.28 μM 21341675
OCI-AML2 cells Proliferation assay Antiproliferative activity against human OCI-AML2 cells, IC50=0.35 μM 21341675
K562 cells Proliferation assay Antiproliferative activity against human K562 cells, IC50=18 μM 21341675
MES-SA Cytotoxicity assay Cytotoxicity against multidrug-resistant human MES-SA cells, IC50=0.005μM. 23937981
MES-SA/Dx5 Cytotoxicity assay Cytotoxicity against human MES-SA/Dx5 cells, IC50=0.005μM. 23937981
Bowes Cytotoxicity assay Cytotoxicity against multidrug-resistant human Bowes cells, IC50=0.01μM. 23937981
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells, IC50=0.02μM. 23937981
Ramos Function assay Induction of Hsp70 production in human Ramos cells after 5 hrs by ELISA, EC50=0.02μM. 23937981
HL60 Cytotoxicity assay Cytotoxicity against multidrug-resistant human HL60 cells, IC50=0.05μM. 23937981
MES-SA Cytotoxicity assay Cytotoxicity against human MES-SA cells, IC50=0.05μM. 23937981
MIP101 Cytotoxicity assay Cytotoxicity against human MIP101 cells, IC50=0.05μM. 23937981
A549 Cytotoxicity assay Cytotoxicity against human A549 cells, IC50=0.1μM. 23937981
Clone A Cytotoxicity assay Cytotoxicity against human Clone A cells, IC50=0.1μM. 23937981
Bowes Cytotoxicity assay Cytotoxicity against wild type human Bowes cells, IC50=0.2μM. 23937981
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells, IC50=0.4μM. 23937981
MDA435 Cytotoxicity assay Cytotoxicity against human MDA435 cells, IC50=5μM. 23937981
MDA-MB-435 Antitumor assay 25 mg/kg Antitumor activity against human MDA-MB-435 cells xenografted in CD-1 nu/nu mouse assessed as tumor regression at 25 mg/kg, iv qod administered 3 times a week for 2 consecutive weeks 23937981
NOS-1 Growth inhibition assay Inhibition of human NOS-1 cell growth in a cell viability assay, IC50=0.0000366μM. SANGER
CAL-51 Growth inhibition assay Inhibition of human CAL-51 cell growth in a cell viability assay, IC50=0.0001264μM. SANGER
ABC-1 Growth inhibition assay Inhibition of human ABC-1 cell growth in a cell viability assay, IC50=0.0003653μM. SANGER
A2780 Growth inhibition assay Inhibition of human A2780 cell growth in a cell viability assay, IC50=0.0005939μM. SANGER
ES1 Growth inhibition assay Inhibition of human ES1 cell growth in a cell viability assay, IC50=0.0007491μM. SANGER
HUTU-80 Growth inhibition assay Inhibition of human HUTU-80 cell growth in a cell viability assay, IC50=0.0007911μM. SANGER
NCI-H292 Growth inhibition assay Inhibition of human NCI-H292 cell growth in a cell viability assay, IC50=0.0008859μM. SANGER
NB69 Growth inhibition assay Inhibition of human NB69 cell growth in a cell viability assay, IC50=0.001218μM. SANGER
ES8 Growth inhibition assay Inhibition of human ES8 cell growth in a cell viability assay, IC50=0.001317μM. SANGER
BCPAP Growth inhibition assay Inhibition of human BCPAP cell growth in a cell viability assay, IC50=0.001345μM. SANGER
T-24 Growth inhibition assay Inhibition of human T-24 cell growth in a cell viability assay, IC50=0.001551μM. SANGER
EW-16 Growth inhibition assay Inhibition of human EW-16 cell growth in a cell viability assay, IC50=0.001609μM. SANGER
OVCAR-5 Growth inhibition assay Inhibition of human OVCAR-5 cell growth in a cell viability assay, IC50=0.001835μM. SANGER
SF126 Growth inhibition assay Inhibition of human SF126 cell growth in a cell viability assay, IC50=0.001954μM. SANGER
KP-4 Growth inhibition assay Inhibition of human KP-4 cell growth in a cell viability assay, IC50=0.002173μM. SANGER
GAMG Growth inhibition assay Inhibition of human GAMG cell growth in a cell viability assay, IC50=0.00251μM. SANGER
HOS Growth inhibition assay Inhibition of human HOS cell growth in a cell viability assay, IC50=0.002531μM. SANGER
CHL-1 Growth inhibition assay Inhibition of human CHL-1 cell growth in a cell viability assay, IC50=0.002811μM. SANGER
AGS Growth inhibition assay Inhibition of human AGS cell growth in a cell viability assay, IC50=0.002863μM. SANGER
MDA-MB-157 Growth inhibition assay Inhibition of human MDA-MB-157 cell growth in a cell viability assay, IC50=0.002918μM. SANGER
HSC-3 Growth inhibition assay Inhibition of human HSC-3 cell growth in a cell viability assay, IC50=0.003015μM. SANGER
CAL-72 Growth inhibition assay Inhibition of human CAL-72 cell growth in a cell viability assay, IC50=0.003023μM. SANGER
NBsusSR Growth inhibition assay Inhibition of human NBsusSR cell growth in a cell viability assay, IC50=0.003134μM. SANGER
ES7 Growth inhibition assay Inhibition of human ES7 cell growth in a cell viability assay, IC50=0.003592μM. SANGER
H-EMC-SS Growth inhibition assay Inhibition of human H-EMC-SS cell growth in a cell viability assay, IC50=0.003684μM. SANGER
NCI-H1703 Growth inhibition assay Inhibition of human NCI-H1703 cell growth in a cell viability assay, IC50=0.003685μM. SANGER
BHT-101 Growth inhibition assay Inhibition of human BHT-101 cell growth in a cell viability assay, IC50=0.00372μM. SANGER
SK-OV-3 Growth inhibition assay Inhibition of human SK-OV-3 cell growth in a cell viability assay, IC50=0.003751μM. SANGER
EW-24 Growth inhibition assay Inhibition of human EW-24 cell growth in a cell viability assay, IC50=0.003835μM. SANGER
PSN1 Growth inhibition assay Inhibition of human PSN1 cell growth in a cell viability assay, IC50=0.003841μM. SANGER
OVCAR-8 Growth inhibition assay Inhibition of human OVCAR-8 cell growth in a cell viability assay, IC50=0.003995μM. SANGER
P12-ICHIKAWA Growth inhibition assay Inhibition of human P12-ICHIKAWA cell growth in a cell viability assay, IC50=0.004044μM. SANGER
SW756 Growth inhibition assay Inhibition of human SW756 cell growth in a cell viability assay, IC50=0.004131μM. SANGER
NCI-H1563 Growth inhibition assay Inhibition of human NCI-H1563 cell growth in a cell viability assay, IC50=0.004133μM. SANGER
A375 Growth inhibition assay Inhibition of human A375 cell growth in a cell viability assay, IC50=0.004143μM. SANGER
Ca9-22 Growth inhibition assay Inhibition of human Ca9-22 cell growth in a cell viability assay, IC50=0.004247μM. SANGER
SW1990 Growth inhibition assay Inhibition of human SW1990 cell growth in a cell viability assay, IC50=0.004318μM. SANGER
ES4 Growth inhibition assay Inhibition of human ES4 cell growth in a cell viability assay, IC50=0.004391μM. SANGER
HCE-T Growth inhibition assay Inhibition of human HCE-T cell growth in a cell viability assay, IC50=0.004451μM. SANGER
MOLT-16 Growth inhibition assay Inhibition of human MOLT-16 cell growth in a cell viability assay, IC50=0.004527μM. SANGER
HSC-4 Growth inhibition assay Inhibition of human HSC-4 cell growth in a cell viability assay, IC50=0.004803μM. SANGER
NCI-SNU-1 Growth inhibition assay Inhibition of human NCI-SNU-1 cell growth in a cell viability assay, IC50=0.004862μM. SANGER
EW-11 Growth inhibition assay Inhibition of human EW-11 cell growth in a cell viability assay, IC50=0.004896μM. SANGER
HT-1080 Growth inhibition assay Inhibition of human HT-1080 cell growth in a cell viability assay, IC50=0.004993μM. SANGER
SW1710 Growth inhibition assay Inhibition of human SW1710 cell growth in a cell viability assay, IC50=0.005164μM. SANGER
EW-1 Growth inhibition assay Inhibition of human EW-1 cell growth in a cell viability assay, IC50=0.005237μM. SANGER
BV-173 Growth inhibition assay Inhibition of human BV-173 cell growth in a cell viability assay, IC50=0.005387μM. SANGER
ChaGo-K-1 Growth inhibition assay Inhibition of human ChaGo-K-1 cell growth in a cell viability assay, IC50=0.0054μM. SANGER
TE-8 Growth inhibition assay Inhibition of human TE-8 cell growth in a cell viability assay, IC50=0.005405μM. SANGER
G-401 Growth inhibition assay Inhibition of human G-401 cell growth in a cell viability assay, IC50=0.005426μM. SANGER
KOSC-2 Growth inhibition assay Inhibition of human KOSC-2 cell growth in a cell viability assay, IC50=0.005453μM. SANGER
HuCCT1 Growth inhibition assay Inhibition of human HuCCT1 cell growth in a cell viability assay, IC50=0.00552μM. SANGER
FADU Growth inhibition assay Inhibition of human FADU cell growth in a cell viability assay, IC50=0.005663μM. SANGER
MHH-ES-1 Growth inhibition assay Inhibition of human MHH-ES-1 cell growth in a cell viability assay, IC50=0.005692μM. SANGER
ES3 Growth inhibition assay Inhibition of human ES3 cell growth in a cell viability assay, IC50=0.005793μM. SANGER
OVCAR-4 Growth inhibition assay Inhibition of human OVCAR-4 cell growth in a cell viability assay, IC50=0.00587μM. SANGER
HD-MY-Z Growth inhibition assay Inhibition of human HD-MY-Z cell growth in a cell viability assay, IC50=0.005909μM. SANGER
JAR Growth inhibition assay Inhibition of human JAR cell growth in a cell viability assay, IC50=0.005967μM. SANGER
A427 Growth inhibition assay Inhibition of human A427 cell growth in a cell viability assay, IC50=0.006067μM. SANGER
697 Growth inhibition assay Inhibition of human 697 cell growth in a cell viability assay, IC50=0.006126μM. SANGER
OVCAR-3 Growth inhibition assay Inhibition of human OVCAR-3 cell growth in a cell viability assay, IC50=0.006201μM. SANGER
NB14 Growth inhibition assay Inhibition of human NB14 cell growth in a cell viability assay, IC50=0.006637μM. SANGER
GB-1 Growth inhibition assay Inhibition of human GB-1 cell growth in a cell viability assay, IC50=0.006709μM. SANGER
COR-L105 Growth inhibition assay Inhibition of human COR-L105 cell growth in a cell viability assay, IC50=0.006764μM. SANGER
647-V Growth inhibition assay Inhibition of human 647-V cell growth in a cell viability assay, IC50=0.006905μM. SANGER
K5 Growth inhibition assay Inhibition of human K5 cell growth in a cell viability assay, IC50=0.006999μM. SANGER
DMS-273 Growth inhibition assay Inhibition of human DMS-273 cell growth in a cell viability assay, IC50=0.007057μM. SANGER
UM-UC-3 Growth inhibition assay Inhibition of human UM-UC-3 cell growth in a cell viability assay, IC50=0.007063μM. SANGER
HEL Growth inhibition assay Inhibition of human HEL cell growth in a cell viability assay, IC50=0.007077μM. SANGER
KU-19-19 Growth inhibition assay Inhibition of human KU-19-19 cell growth in a cell viability assay, IC50=0.007094μM. SANGER
MC-IXC Growth inhibition assay Inhibition of human MC-IXC cell growth in a cell viability assay, IC50=0.007171μM. SANGER
H4 Growth inhibition assay Inhibition of human H4 cell growth in a cell viability assay, IC50=0.00725μM. SANGER
NUGC-3 Growth inhibition assay Inhibition of human NUGC-3 cell growth in a cell viability assay, IC50=0.007328μM. SANGER
CHP-212 Growth inhibition assay Inhibition of human CHP-212 cell growth in a cell viability assay, IC50=0.007342μM. SANGER
SW982 Growth inhibition assay Inhibition of human SW982 cell growth in a cell viability assay, IC50=0.00744μM. SANGER
C-33-A Growth inhibition assay Inhibition of human C-33-A cell growth in a cell viability assay, IC50=0.007579μM. SANGER
HGC-27 Growth inhibition assay Inhibition of human HGC-27 cell growth in a cell viability assay, IC50=0.007592μM. SANGER
VA-ES-BJ Growth inhibition assay Inhibition of human VA-ES-BJ cell growth in a cell viability assay, IC50=0.007641μM. SANGER
SW13 Growth inhibition assay Inhibition of human SW13 cell growth in a cell viability assay, IC50=0.007689μM. SANGER
EFO-27 Growth inhibition assay Inhibition of human EFO-27 cell growth in a cell viability assay, IC50=0.007718μM. SANGER
LNCaP-Clone-FGC Growth inhibition assay Inhibition of human LNCaP-Clone-FGC cell growth in a cell viability assay, IC50=0.007726μM. SANGER
PC-3 Growth inhibition assay Inhibition of human PC-3 cell growth in a cell viability assay, IC50=0.007885μM. SANGER
HEC-1 Growth inhibition assay Inhibition of human HEC-1 cell growth in a cell viability assay, IC50=0.008254μM. SANGER
GI-1 Growth inhibition assay Inhibition of human GI-1 cell growth in a cell viability assay, IC50=0.008261μM. SANGER
EGI-1 Growth inhibition assay Inhibition of human EGI-1 cell growth in a cell viability assay, IC50=0.008376μM. SANGER
HCC1395 Growth inhibition assay Inhibition of human HCC1395 cell growth in a cell viability assay, IC50=0.008469μM. SANGER
RERF-LC-MS Growth inhibition assay Inhibition of human RERF-LC-MS cell growth in a cell viability assay, IC50=0.008579μM. SANGER
CP50-MEL-B Growth inhibition assay Inhibition of human CP50-MEL-B cell growth in a cell viability assay, IC50=0.008626μM. SANGER
CTB-1 Growth inhibition assay Inhibition of human CTB-1 cell growth in a cell viability assay, IC50=0.00864μM. SANGER
JEG-3 Growth inhibition assay Inhibition of human JEG-3 cell growth in a cell viability assay, IC50=0.00884μM. SANGER
PA-1 Growth inhibition assay Inhibition of human PA-1 cell growth in a cell viability assay, IC50=0.008844μM. SANGER
A204 Growth inhibition assay Inhibition of human A204 cell growth in a cell viability assay, IC50=0.008848μM. SANGER
NCI-H1355 Growth inhibition assay Inhibition of human NCI-H1355 cell growth in a cell viability assay, IC50=0.008886μM. SANGER
NB17 Growth inhibition assay Inhibition of human NB17 cell growth in a cell viability assay, IC50=0.008939μM. SANGER
SK-PN-DW Growth inhibition assay Inhibition of human SK-PN-DW cell growth in a cell viability assay, IC50=0.009023μM. SANGER
NCI-H1693 Growth inhibition assay Inhibition of human NCI-H1693 cell growth in a cell viability assay, IC50=0.009094μM. SANGER
MPP-89 Growth inhibition assay Inhibition of human MPP-89 cell growth in a cell viability assay, IC50=0.009133μM. SANGER
8-MG-BA Growth inhibition assay Inhibition of human 8-MG-BA cell growth in a cell viability assay, IC50=0.00914μM. SANGER
SF295 Growth inhibition assay Inhibition of human SF295 cell growth in a cell viability assay, IC50=0.009195μM. SANGER
COLO-684 Growth inhibition assay Inhibition of human COLO-684 cell growth in a cell viability assay, IC50=0.009208μM. SANGER
DMS-114 Growth inhibition assay Inhibition of human DMS-114 cell growth in a cell viability assay, IC50=0.009431μM. SANGER
SNU-387 Growth inhibition assay Inhibition of human SNU-387 cell growth in a cell viability assay, IC50=0.00949μM. SANGER
KNS-62 Growth inhibition assay Inhibition of human KNS-62 cell growth in a cell viability assay, IC50=0.009619μM. SANGER
PANC-08-13 Growth inhibition assay Inhibition of human PANC-08-13 cell growth in a cell viability assay, IC50=0.009634μM. SANGER
DBTRG-05MG Growth inhibition assay Inhibition of human DBTRG-05MG cell growth in a cell viability assay, IC50=0.009769μM. SANGER
769-P Growth inhibition assay Inhibition of human 769-P cell growth in a cell viability assay, IC50=0.009821μM. SANGER
U251 Growth inhibition assay Inhibition of human U251 cell growth in a cell viability assay, IC50=0.009856μM. SANGER
HLE Growth inhibition assay Inhibition of human HLE cell growth in a cell viability assay, IC50=0.009925μM. SANGER
ONS-76 Growth inhibition assay Inhibition of human ONS-76 cell growth in a cell viability assay, IC50=0.01026μM. SANGER
SK-LU-1 Growth inhibition assay Inhibition of human SK-LU-1 cell growth in a cell viability assay, IC50=0.01034μM. SANGER
8505C Growth inhibition assay Inhibition of human 8505C cell growth in a cell viability assay, IC50=0.01053μM. SANGER
MEL-JUSO Growth inhibition assay Inhibition of human MEL-JUSO cell growth in a cell viability assay, IC50=0.01064μM. SANGER
SW1573 Growth inhibition assay Inhibition of human SW1573 cell growth in a cell viability assay, IC50=0.01068μM. SANGER
LB1047-RCC Growth inhibition assay Inhibition of human LB1047-RCC cell growth in a cell viability assay, IC50=0.01075μM. SANGER
AN3-CA Growth inhibition assay Inhibition of human AN3-CA cell growth in a cell viability assay, IC50=0.01079μM. SANGER
CGTH-W-1 Growth inhibition assay Inhibition of human CGTH-W-1 cell growth in a cell viability assay, IC50=0.01095μM. SANGER
Saos-2 Growth inhibition assay Inhibition of human Saos-2 cell growth in a cell viability assay, IC50=0.01108μM. SANGER
22RV1 Growth inhibition assay Inhibition of human 22RV1 cell growth in a cell viability assay, IC50=0.0113μM. SANGER
IST-MEL1 Growth inhibition assay Inhibition of human IST-MEL1 cell growth in a cell viability assay, IC50=0.01134μM. SANGER
A101D Growth inhibition assay Inhibition of human A101D cell growth in a cell viability assay, IC50=0.01142μM. SANGER
MHH-PREB-1 Growth inhibition assay Inhibition of human MHH-PREB-1 cell growth in a cell viability assay, IC50=0.01145μM. SANGER
NEC8 Growth inhibition assay Inhibition of human NEC8 cell growth in a cell viability assay, IC50=0.01149μM. SANGER
A673 Growth inhibition assay Inhibition of human A673 cell growth in a cell viability assay, IC50=0.0116μM. SANGER
ACN Growth inhibition assay Inhibition of human ACN cell growth in a cell viability assay, IC50=0.01172μM. SANGER
ES5 Growth inhibition assay Inhibition of human ES5 cell growth in a cell viability assay, IC50=0.0118μM. SANGER
Ramos-2G6-4C10 Growth inhibition assay Inhibition of human Ramos-2G6-4C10 cell growth in a cell viability assay, IC50=0.01199μM. SANGER
D-423MG Growth inhibition assay Inhibition of human D-423MG cell growth in a cell viability assay, IC50=0.01199μM. SANGER
NCI-H23 Growth inhibition assay Inhibition of human NCI-H23 cell growth in a cell viability assay, IC50=0.01222μM. SANGER
L-363 Growth inhibition assay Inhibition of human L-363 cell growth in a cell viability assay, IC50=0.01227μM. SANGER
SJSA-1 Growth inhibition assay Inhibition of human SJSA-1 cell growth in a cell viability assay, IC50=0.01233μM. SANGER
NCI-H510A Growth inhibition assay Inhibition of human NCI-H510A cell growth in a cell viability assay, IC50=0.01239μM. SANGER
TYK-nu Growth inhibition assay Inhibition of human TYK-nu cell growth in a cell viability assay, IC50=0.01239μM. SANGER
NCI-H661 Growth inhibition assay Inhibition of human NCI-H661 cell growth in a cell viability assay, IC50=0.01247μM. SANGER
YKG-1 Growth inhibition assay Inhibition of human YKG-1 cell growth in a cell viability assay, IC50=0.01256μM. SANGER
VM-CUB-1 Growth inhibition assay Inhibition of human VM-CUB-1 cell growth in a cell viability assay, IC50=0.01267μM. SANGER
PFSK-1 Growth inhibition assay Inhibition of human PFSK-1 cell growth in a cell viability assay, IC50=0.01268μM. SANGER
MZ7-mel Growth inhibition assay Inhibition of human MZ7-mel cell growth in a cell viability assay, IC50=0.01271μM. SANGER
HOP-92 Growth inhibition assay Inhibition of human HOP-92 cell growth in a cell viability assay, IC50=0.01272μM. SANGER
SF268 Growth inhibition assay Inhibition of human SF268 cell growth in a cell viability assay, IC50=0.01286μM. SANGER
786-0 Growth inhibition assay Inhibition of human 786-0 cell growth in a cell viability assay, IC50=0.01287μM. SANGER
TGBC24TKB Growth inhibition assay Inhibition of human TGBC24TKB cell growth in a cell viability assay, IC50=0.01292μM. SANGER
HT-144 Growth inhibition assay Inhibition of human HT-144 cell growth in a cell viability assay, IC50=0.01303μM. SANGER
RD Growth inhibition assay Inhibition of human RD cell growth in a cell viability assay, IC50=0.01311μM. SANGER
CAL-39 Growth inhibition assay Inhibition of human CAL-39 cell growth in a cell viability assay, IC50=0.01329μM. SANGER
NCI-H1755 Growth inhibition assay Inhibition of human NCI-H1755 cell growth in a cell viability assay, IC50=0.01333μM. SANGER
U031 Growth inhibition assay Inhibition of human U031 cell growth in a cell viability assay, IC50=0.01342μM. SANGER
RXF393 Growth inhibition assay Inhibition of human RXF393 cell growth in a cell viability assay, IC50=0.01344μM. SANGER
TCCSUP Growth inhibition assay Inhibition of human TCCSUP cell growth in a cell viability assay, IC50=0.01346μM. SANGER
MLMA Growth inhibition assay Inhibition of human MLMA cell growth in a cell viability assay, IC50=0.01358μM. SANGER
NCI-H1395 Growth inhibition assay Inhibition of human NCI-H1395 cell growth in a cell viability assay, IC50=0.01358μM. SANGER
NCI-H358 Growth inhibition assay Inhibition of human NCI-H358 cell growth in a cell viability assay, IC50=0.01365μM. SANGER
NCI-H28 Growth inhibition assay Inhibition of human NCI-H28 cell growth in a cell viability assay, IC50=0.01369μM. SANGER
KS-1 Growth inhibition assay Inhibition of human KS-1 cell growth in a cell viability assay, IC50=0.01378μM. SANGER
A2058 Growth inhibition assay Inhibition of human A2058 cell growth in a cell viability assay, IC50=0.01385μM. SANGER
CAL-120 Growth inhibition assay Inhibition of human CAL-120 cell growth in a cell viability assay, IC50=0.01395μM. SANGER
MKN28 Growth inhibition assay Inhibition of human MKN28 cell growth in a cell viability assay, IC50=0.01398μM. SANGER
LXF-289 Growth inhibition assay Inhibition of human LXF-289 cell growth in a cell viability assay, IC50=0.01404μM. SANGER
SK-UT-1 Growth inhibition assay Inhibition of human SK-UT-1 cell growth in a cell viability assay, IC50=0.01409μM. SANGER
J82 Growth inhibition assay Inhibition of human J82 cell growth in a cell viability assay, IC50=0.01413μM. SANGER
COLO-679 Growth inhibition assay Inhibition of human COLO-679 cell growth in a cell viability assay, IC50=0.01414μM. SANGER
SNU-449 Growth inhibition assay Inhibition of human SNU-449 cell growth in a cell viability assay, IC50=0.01419μM. SANGER
SW954 Growth inhibition assay Inhibition of human SW954 cell growth in a cell viability assay, IC50=0.01421μM. SANGER
RT-112 Growth inhibition assay Inhibition of human RT-112 cell growth in a cell viability assay, IC50=0.01423μM. SANGER
MN-60 Growth inhibition assay Inhibition of human MN-60 cell growth in a cell viability assay, IC50=0.01428μM. SANGER
J-RT3-T3-5 Growth inhibition assay Inhibition of human J-RT3-T3-5 cell growth in a cell viability assay, IC50=0.01439μM. SANGER
NB7 Growth inhibition assay Inhibition of human NB7 cell growth in a cell viability assay, IC50=0.01439μM. SANGER
LB373-MEL-D Growth inhibition assay Inhibition of human LB373-MEL-D cell growth in a cell viability assay, IC50=0.01467μM. SANGER
TE-5 Growth inhibition assay Inhibition of human TE-5 cell growth in a cell viability assay, IC50=0.01504μM. SANGER
SNU-423 Growth inhibition assay Inhibition of human SNU-423 cell growth in a cell viability assay, IC50=0.01515μM. SANGER
NB10 Growth inhibition assay Inhibition of human NB10 cell growth in a cell viability assay, IC50=0.01517μM. SANGER
TI-73 Growth inhibition assay Inhibition of human TI-73 cell growth in a cell viability assay, IC50=0.01522μM. SANGER
D-566MG Growth inhibition assay Inhibition of human D-566MG cell growth in a cell viability assay, IC50=0.01523μM. SANGER
HN Growth inhibition assay Inhibition of human HN cell growth in a cell viability assay, IC50=0.01538μM. SANGER
Hs-578-T Growth inhibition assay Inhibition of human Hs-578-T cell growth in a cell viability assay, IC50=0.01554μM. SANGER
U-266 Growth inhibition assay Inhibition of human U-266 cell growth in a cell viability assay, IC50=0.01582μM. SANGER
BT-549 Growth inhibition assay Inhibition of human BT-549 cell growth in a cell viability assay, IC50=0.01583μM. SANGER
GT3TKB Growth inhibition assay Inhibition of human GT3TKB cell growth in a cell viability assay, IC50=0.016μM. SANGER
G-402 Growth inhibition assay Inhibition of human G-402 cell growth in a cell viability assay, IC50=0.01617μM. SANGER
ME-180 Growth inhibition assay Inhibition of human ME-180 cell growth in a cell viability assay, IC50=0.01624μM. SANGER
NCI-H2126 Growth inhibition assay Inhibition of human NCI-H2126 cell growth in a cell viability assay, IC50=0.01631μM. SANGER
639-V Growth inhibition assay Inhibition of human 639-V cell growth in a cell viability assay, IC50=0.01674μM. SANGER
T47D Growth inhibition assay Inhibition of human T47D cell growth in a cell viability assay, IC50=0.01679μM. SANGER
Daoy Growth inhibition assay Inhibition of human Daoy cell growth in a cell viability assay, IC50=0.0168μM. SANGER
DK-MG Growth inhibition assay Inhibition of human DK-MG cell growth in a cell viability assay, IC50=0.01706μM. SANGER
MIA-PaCa-2 Growth inhibition assay Inhibition of human MIA-PaCa-2 cell growth in a cell viability assay, IC50=0.01711μM. SANGER
KNS-81-FD Growth inhibition assay Inhibition of human KNS-81-FD cell growth in a cell viability assay, IC50=0.01746μM. SANGER
HuH-7 Growth inhibition assay Inhibition of human HuH-7 cell growth in a cell viability assay, IC50=0.01764μM. SANGER
DOK Growth inhibition assay Inhibition of human DOK cell growth in a cell viability assay, IC50=0.01792μM. SANGER
MV-4-11 Growth inhibition assay Inhibition of human MV-4-11 cell growth in a cell viability assay, IC50=0.018μM. SANGER
NCI-H1048 Growth inhibition assay Inhibition of human NCI-H1048 cell growth in a cell viability assay, IC50=0.01835μM. SANGER
NCI-H1299 Growth inhibition assay Inhibition of human NCI-H1299 cell growth in a cell viability assay, IC50=0.01854μM. SANGER
GOTO Growth inhibition assay Inhibition of human GOTO cell growth in a cell viability assay, IC50=0.01865μM. SANGER
MDA-MB-231 Growth inhibition assay Inhibition of human MDA-MB-231 cell growth in a cell viability assay, IC50=0.01904μM. SANGER
BT-474 Growth inhibition assay Inhibition of human BT-474 cell growth in a cell viability assay, IC50=0.01921μM. SANGER
DEL Growth inhibition assay Inhibition of human DEL cell growth in a cell viability assay, IC50=0.01922μM. SANGER
NTERA-S-cl-D1 Growth inhibition assay Inhibition of human NTERA-S-cl-D1 cell growth in a cell viability assay, IC50=0.01939μM. SANGER
HCC1419 Growth inhibition assay Inhibition of human HCC1419 cell growth in a cell viability assay, IC50=0.01959μM. SANGER
A549 Growth inhibition assay Inhibition of human A549 cell growth in a cell viability assay, IC50=0.0196μM. SANGER
LK-2 Growth inhibition assay Inhibition of human LK-2 cell growth in a cell viability assay, IC50=0.01969μM. SANGER
KYSE-410 Growth inhibition assay Inhibition of human KYSE-410 cell growth in a cell viability assay, IC50=0.0197μM. SANGER
U-2-OS Growth inhibition assay Inhibition of human U-2-OS cell growth in a cell viability assay, IC50=0.01973μM. SANGER
EW-13 Growth inhibition assay Inhibition of human EW-13 cell growth in a cell viability assay, IC50=0.01975μM. SANGER
NMC-G1 Growth inhibition assay Inhibition of human NMC-G1 cell growth in a cell viability assay, IC50=0.02039μM. SANGER
BFTC-905 Growth inhibition assay Inhibition of human BFTC-905 cell growth in a cell viability assay, IC50=0.02046μM. SANGER
M059J Growth inhibition assay Inhibition of human M059J cell growth in a cell viability assay, IC50=0.02055μM. SANGER
HuP-T4 Growth inhibition assay Inhibition of human HuP-T4 cell growth in a cell viability assay, IC50=0.02073μM. SANGER
A172 Growth inhibition assay Inhibition of human A172 cell growth in a cell viability assay, IC50=0.02089μM. SANGER
RKO Growth inhibition assay Inhibition of human RKO cell growth in a cell viability assay, IC50=0.02098μM. SANGER
KYSE-140 Growth inhibition assay Inhibition of human KYSE-140 cell growth in a cell viability assay, IC50=0.02099μM. SANGER
HuO9 Growth inhibition assay Inhibition of human HuO9 cell growth in a cell viability assay, IC50=0.02154μM. SANGER
SBC-5 Growth inhibition assay Inhibition of human SBC-5 cell growth in a cell viability assay, IC50=0.02162μM. SANGER
NCI-H2452 Growth inhibition assay Inhibition of human NCI-H2452 cell growth in a cell viability assay, IC50=0.02172μM. SANGER
HT-1197 Growth inhibition assay Inhibition of human HT-1197 cell growth in a cell viability assay, IC50=0.02182μM. SANGER
UACC-257 Growth inhibition assay Inhibition of human UACC-257 cell growth in a cell viability assay, IC50=0.02197μM. SANGER
CAL-33 Growth inhibition assay Inhibition of human CAL-33 cell growth in a cell viability assay, IC50=0.02223μM. SANGER
Becker Growth inhibition assay Inhibition of human Becker cell growth in a cell viability assay, IC50=0.02227μM. SANGER
SAS Growth inhibition assay Inhibition of human SAS cell growth in a cell viability assay, IC50=0.0225μM. SANGER
SCC-25 Growth inhibition assay Inhibition of human SCC-25 cell growth in a cell viability assay, IC50=0.02296μM. SANGER
NB13 Growth inhibition assay Inhibition of human NB13 cell growth in a cell viability assay, IC50=0.02311μM. SANGER
UACC-62 Growth inhibition assay Inhibition of human UACC-62 cell growth in a cell viability assay, IC50=0.02319μM. SANGER
no-11 Growth inhibition assay Inhibition of human no-11 cell growth in a cell viability assay, IC50=0.02328μM. SANGER
DSH1 Growth inhibition assay Inhibition of human DSH1 cell growth in a cell viability assay, IC50=0.02332μM. SANGER
GCT Growth inhibition assay Inhibition of human GCT cell growth in a cell viability assay, IC50=0.02339μM. SANGER
D-336MG Growth inhibition assay Inhibition of human D-336MG cell growth in a cell viability assay, IC50=0.02343μM. SANGER
HCC1806 Growth inhibition assay Inhibition of human HCC1806 cell growth in a cell viability assay, IC50=0.02348μM. SANGER
KYSE-180 Growth inhibition assay Inhibition of human KYSE-180 cell growth in a cell viability assay, IC50=0.02384μM. SANGER
HuO-3N1 Growth inhibition assay Inhibition of human HuO-3N1 cell growth in a cell viability assay, IC50=0.02396μM. SANGER
CAKI-1 Growth inhibition assay Inhibition of human CAKI-1 cell growth in a cell viability assay, IC50=0.02412μM. SANGER
YH-13 Growth inhibition assay Inhibition of human YH-13 cell growth in a cell viability assay, IC50=0.02415μM. SANGER
BB65-RCC Growth inhibition assay Inhibition of human BB65-RCC cell growth in a cell viability assay, IC50=0.02416μM. SANGER
SF539 Growth inhibition assay Inhibition of human SF539 cell growth in a cell viability assay, IC50=0.02437μM. SANGER
HO-1-N-1 Growth inhibition assay Inhibition of human HO-1-N-1 cell growth in a cell viability assay, IC50=0.0245μM. SANGER
NCI-H1581 Growth inhibition assay Inhibition of human NCI-H1581 cell growth in a cell viability assay, IC50=0.02462μM. SANGER
PC-14 Growth inhibition assay Inhibition of human PC-14 cell growth in a cell viability assay, IC50=0.02473μM. SANGER
D-247MG Growth inhibition assay Inhibition of human D-247MG cell growth in a cell viability assay, IC50=0.02473μM. SANGER
23132-87 Growth inhibition assay Inhibition of human 23132-87 cell growth in a cell viability assay, IC50=0.02492μM. SANGER
SCC-15 Growth inhibition assay Inhibition of human SCC-15 cell growth in a cell viability assay, IC50=0.02563μM. SANGER
D-502MG Growth inhibition assay Inhibition of human D-502MG cell growth in a cell viability assay, IC50=0.02581μM. SANGER
MDA-MB-361 Growth inhibition assay Inhibition of human MDA-MB-361 cell growth in a cell viability assay, IC50=0.02589μM. SANGER
MKN1 Growth inhibition assay Inhibition of human MKN1 cell growth in a cell viability assay, IC50=0.02597μM. SANGER
RO82-W-1 Growth inhibition assay Inhibition of human RO82-W-1 cell growth in a cell viability assay, IC50=0.02622μM. SANGER
Mewo Growth inhibition assay Inhibition of human Mewo cell growth in a cell viability assay, IC50=0.02629μM. SANGER
C32 Growth inhibition assay Inhibition of human C32 cell growth in a cell viability assay, IC50=0.0263μM. SANGER
NCI-H2030 Growth inhibition assay Inhibition of human NCI-H2030 cell growth in a cell viability assay, IC50=0.02636μM. SANGER
FTC-133 Growth inhibition assay Inhibition of human FTC-133 cell growth in a cell viability assay, IC50=0.02701μM. SANGER
S-117 Growth inhibition assay Inhibition of human S-117 cell growth in a cell viability assay, IC50=0.02741μM. SANGER
A704 Growth inhibition assay Inhibition of human A704 cell growth in a cell viability assay, IC50=0.02745μM. SANGER
G-361 Growth inhibition assay Inhibition of human G-361 cell growth in a cell viability assay, IC50=0.02754μM. SANGER
LB831-BLC Growth inhibition assay Inhibition of human LB831-BLC cell growth in a cell viability assay, IC50=0.02772μM. SANGER
LC-2-ad Growth inhibition assay Inhibition of human LC-2-ad cell growth in a cell viability assay, IC50=0.02781μM. SANGER
SN12C Growth inhibition assay Inhibition of human SN12C cell growth in a cell viability assay, IC50=0.02843μM. SANGER
MKN45 Growth inhibition assay Inhibition of human MKN45 cell growth in a cell viability assay, IC50=0.02868μM. SANGER
NCI-H2347 Growth inhibition assay Inhibition of human NCI-H2347 cell growth in a cell viability assay, IC50=0.02874μM. SANGER
COLO-792 Growth inhibition assay Inhibition of human COLO-792 cell growth in a cell viability assay, IC50=0.02877μM. SANGER
NCI-H2170 Growth inhibition assay Inhibition of human NCI-H2170 cell growth in a cell viability assay, IC50=0.02885μM. SANGER
EPLC-272H Growth inhibition assay Inhibition of human EPLC-272H cell growth in a cell viability assay, IC50=0.02913μM. SANGER
COLO-800 Growth inhibition assay Inhibition of human COLO-800 cell growth in a cell viability assay, IC50=0.02992μM. SANGER
RPMI-8866 Growth inhibition assay Inhibition of human RPMI-8866 cell growth in a cell viability assay, IC50=0.03002μM. SANGER
SK-N-AS Growth inhibition assay Inhibition of human SK-N-AS cell growth in a cell viability assay, IC50=0.03004μM. SANGER
SW780 Growth inhibition assay Inhibition of human SW780 cell growth in a cell viability assay, IC50=0.03032μM. SANGER
HTC-C3 Growth inhibition assay Inhibition of human HTC-C3 cell growth in a cell viability assay, IC50=0.03039μM. SANGER
NCI-H1650 Growth inhibition assay Inhibition of human NCI-H1650 cell growth in a cell viability assay, IC50=0.03043μM. SANGER
NB5 Growth inhibition assay Inhibition of human NB5 cell growth in a cell viability assay, IC50=0.03066μM. SANGER
NCI-H2228 Growth inhibition assay Inhibition of human NCI-H2228 cell growth in a cell viability assay, IC50=0.03091μM. SANGER
SiHa Growth inhibition assay Inhibition of human SiHa cell growth in a cell viability assay, IC50=0.03106μM. SANGER
MCF7 Growth inhibition assay Inhibition of human MCF7 cell growth in a cell viability assay, IC50=0.03136μM. SANGER
QIMR-WIL Growth inhibition assay Inhibition of human QIMR-WIL cell growth in a cell viability assay, IC50=0.03293μM. SANGER
TGBC1TKB Growth inhibition assay Inhibition of human TGBC1TKB cell growth in a cell viability assay, IC50=0.03331μM. SANGER
CAL-27 Growth inhibition assay Inhibition of human CAL-27 cell growth in a cell viability assay, IC50=0.0334μM. SANGER
OC-314 Growth inhibition assay Inhibition of human OC-314 cell growth in a cell viability assay, IC50=0.03348μM. SANGER
WM-115 Growth inhibition assay Inhibition of human WM-115 cell growth in a cell viability assay, IC50=0.03401μM. SANGER
RPMI-2650 Growth inhibition assay Inhibition of human RPMI-2650 cell growth in a cell viability assay, IC50=0.03413μM. SANGER
T98G Growth inhibition assay Inhibition of human T98G cell growth in a cell viability assay, IC50=0.03431μM. SANGER
MDA-MB-453 Growth inhibition assay Inhibition of human MDA-MB-453 cell growth in a cell viability assay, IC50=0.03469μM. SANGER
ETK-1 Growth inhibition assay Inhibition of human ETK-1 cell growth in a cell viability assay, IC50=0.03502μM. SANGER
SBC-1 Growth inhibition assay Inhibition of human SBC-1 cell growth in a cell viability assay, IC50=0.03508μM. SANGER
HCC1937 Growth inhibition assay Inhibition of human HCC1937 cell growth in a cell viability assay, IC50=0.03516μM. SANGER
BT-20 Growth inhibition assay Inhibition of human BT-20 cell growth in a cell viability assay, IC50=0.03521μM. SANGER
BB30-HNC Growth inhibition assay Inhibition of human BB30-HNC cell growth in a cell viability assay, IC50=0.03535μM. SANGER
5637 Growth inhibition assay Inhibition of human 5637 cell growth in a cell viability assay, IC50=0.03546μM. SANGER
NCI-H650 Growth inhibition assay Inhibition of human NCI-H650 cell growth in a cell viability assay, IC50=0.03656μM. SANGER
RPMI-7951 Growth inhibition assay Inhibition of human RPMI-7951 cell growth in a cell viability assay, IC50=0.03657μM. SANGER
KYSE-270 Growth inhibition assay Inhibition of human KYSE-270 cell growth in a cell viability assay, IC50=0.03709μM. SANGER
KARPAS-299 Growth inhibition assay Inhibition of human KARPAS-299 cell growth in a cell viability assay, IC50=0.03737μM. SANGER
NY Growth inhibition assay Inhibition of human NY cell growth in a cell viability assay, IC50=0.0376μM. SANGER
AsPC-1 Growth inhibition assay Inhibition of human AsPC-1 cell growth in a cell viability assay, IC50=0.0377μM. SANGER
HPAF-II Growth inhibition assay Inhibition of human HPAF-II cell growth in a cell viability assay, IC50=0.03827μM. SANGER
KYSE-450 Growth inhibition assay Inhibition of human KYSE-450 cell growth in a cell viability assay, IC50=0.03897μM. SANGER
EKVX Growth inhibition assay Inhibition of human EKVX cell growth in a cell viability assay, IC50=0.03951μM. SANGER
KG-1 Growth inhibition assay Inhibition of human KG-1 cell growth in a cell viability assay, IC50=0.03969μM. SANGER
EW-3 Growth inhibition assay Inhibition of human EW-3 cell growth in a cell viability assay, IC50=0.03988μM. SANGER
PANC-03-27 Growth inhibition assay Inhibition of human PANC-03-27 cell growth in a cell viability assay, IC50=0.03991μM. SANGER
ES6 Growth inhibition assay Inhibition of human ES6 cell growth in a cell viability assay, IC50=0.03997μM. SANGER
HCT-116 Growth inhibition assay Inhibition of human HCT-116 cell growth in a cell viability assay, IC50=0.04003μM. SANGER
SW620 Growth inhibition assay Inhibition of human SW620 cell growth in a cell viability assay, IC50=0.04073μM. SANGER
D-283MED Growth inhibition assay Inhibition of human D-283MED cell growth in a cell viability assay, IC50=0.04085μM. SANGER
TK10 Growth inhibition assay Inhibition of human TK10 cell growth in a cell viability assay, IC50=0.04233μM. SANGER
COLO-678 Growth inhibition assay Inhibition of human COLO-678 cell growth in a cell viability assay, IC50=0.04253μM. SANGER
COLO-829 Growth inhibition assay Inhibition of human COLO-829 cell growth in a cell viability assay, IC50=0.04311μM. SANGER
NCI-H2342 Growth inhibition assay Inhibition of human NCI-H2342 cell growth in a cell viability assay, IC50=0.04327μM. SANGER
EC-GI-10 Growth inhibition assay Inhibition of human EC-GI-10 cell growth in a cell viability assay, IC50=0.04463μM. SANGER
NCI-H596 Growth inhibition assay Inhibition of human NCI-H596 cell growth in a cell viability assay, IC50=0.04484μM. SANGER
MFM-223 Growth inhibition assay Inhibition of human MFM-223 cell growth in a cell viability assay, IC50=0.0452μM. SANGER
TE-1 Growth inhibition assay Inhibition of human TE-1 cell growth in a cell viability assay, IC50=0.04597μM. SANGER
RPMI-8226 Growth inhibition assay Inhibition of human RPMI-8226 cell growth in a cell viability assay, IC50=0.04599μM. SANGER
TE-11 Growth inhibition assay Inhibition of human TE-11 cell growth in a cell viability assay, IC50=0.04613μM. SANGER
NCI-H1155 Growth inhibition assay Inhibition of human NCI-H1155 cell growth in a cell viability assay, IC50=0.04621μM. SANGER
A498 Growth inhibition assay Inhibition of human A498 cell growth in a cell viability assay, IC50=0.04655μM. SANGER
OS-RC-2 Growth inhibition assay Inhibition of human OS-RC-2 cell growth in a cell viability assay, IC50=0.04771μM. SANGER
ZR-75-30 Growth inhibition assay Inhibition of human ZR-75-30 cell growth in a cell viability assay, IC50=0.04788μM. SANGER
NB12 Growth inhibition assay Inhibition of human NB12 cell growth in a cell viability assay, IC50=0.04796μM. SANGER
LS-123 Growth inhibition assay Inhibition of human LS-123 cell growth in a cell viability assay, IC50=0.04849μM. SANGER
SKG-IIIa Growth inhibition assay Inhibition of human SKG-IIIa cell growth in a cell viability assay, IC50=0.04982μM. SANGER
NCI-H2405 Growth inhibition assay Inhibition of human NCI-H2405 cell growth in a cell viability assay, IC50=0.05105μM. SANGER
IST-SL1 Growth inhibition assay Inhibition of human IST-SL1 cell growth in a cell viability assay, IC50=0.05232μM. SANGER
LAMA-84 Growth inhibition assay Inhibition of human LAMA-84 cell growth in a cell viability assay, IC50=0.05267μM. SANGER
HCC70 Growth inhibition assay Inhibition of human HCC70 cell growth in a cell viability assay, IC50=0.05309μM. SANGER
SW626 Growth inhibition assay Inhibition of human SW626 cell growth in a cell viability assay, IC50=0.05398μM. SANGER
KYSE-70 Growth inhibition assay Inhibition of human KYSE-70 cell growth in a cell viability assay, IC50=0.05405μM. SANGER
IST-MES1 Growth inhibition assay Inhibition of human IST-MES1 cell growth in a cell viability assay, IC50=0.05415μM. SANGER
DJM-1 Growth inhibition assay Inhibition of human DJM-1 cell growth in a cell viability assay, IC50=0.0543μM. SANGER
LAN-6 Growth inhibition assay Inhibition of human LAN-6 cell growth in a cell viability assay, IC50=0.05459μM. SANGER
CP66-MEL Growth inhibition assay Inhibition of human CP66-MEL cell growth in a cell viability assay, IC50=0.05515μM. SANGER
CAL-62 Growth inhibition assay Inhibition of human CAL-62 cell growth in a cell viability assay, IC50=0.05519μM. SANGER
HuP-T3 Growth inhibition assay Inhibition of human HuP-T3 cell growth in a cell viability assay, IC50=0.05575μM. SANGER
LB2241-RCC Growth inhibition assay Inhibition of human LB2241-RCC cell growth in a cell viability assay, IC50=0.05636μM. SANGER
NCI-H747 Growth inhibition assay Inhibition of human NCI-H747 cell growth in a cell viability assay, IC50=0.0574μM. SANGER
H9 Growth inhibition assay Inhibition of human H9 cell growth in a cell viability assay, IC50=0.05813μM. SANGER
RH-1 Growth inhibition assay Inhibition of human RH-1 cell growth in a cell viability assay, IC50=0.05817μM. SANGER
AU565 Growth inhibition assay Inhibition of human AU565 cell growth in a cell viability assay, IC50=0.05907μM. SANGER
HCE-4 Growth inhibition assay Inhibition of human HCE-4 cell growth in a cell viability assay, IC50=0.0591μM. SANGER
MKN7 Growth inhibition assay Inhibition of human MKN7 cell growth in a cell viability assay, IC50=0.061μM. SANGER
EoL-1-cell Growth inhibition assay Inhibition of human EoL-1-cell cell growth in a cell viability assay, IC50=0.06203μM. SANGER
SW900 Growth inhibition assay Inhibition of human SW900 cell growth in a cell viability assay, IC50=0.06212μM. SANGER
CAL-12T Growth inhibition assay Inhibition of human CAL-12T cell growth in a cell viability assay, IC50=0.063μM. SANGER
NCI-H2052 Growth inhibition assay Inhibition of human NCI-H2052 cell growth in a cell viability assay, IC50=0.06331μM. SANGER
BFTC-909 Growth inhibition assay Inhibition of human BFTC-909 cell growth in a cell viability assay, IC50=0.0635μM. SANGER
KP-N-YN Growth inhibition assay Inhibition of human KP-N-YN cell growth in a cell viability assay, IC50=0.06561μM. SANGER
HL-60 Growth inhibition assay Inhibition of human HL-60 cell growth in a cell viability assay, IC50=0.06677μM. SANGER
LB2518-MEL Growth inhibition assay Inhibition of human LB2518-MEL cell growth in a cell viability assay, IC50=0.06694μM. SANGER
Detroit562 Growth inhibition assay Inhibition of human Detroit562 cell growth in a cell viability assay, IC50=0.0689μM. SANGER
MHH-NB-11 Growth inhibition assay Inhibition of human MHH-NB-11 cell growth in a cell viability assay, IC50=0.06913μM. SANGER
YAPC Growth inhibition assay Inhibition of human YAPC cell growth in a cell viability assay, IC50=0.07034μM. SANGER
COLO-824 Growth inhibition assay Inhibition of human COLO-824 cell growth in a cell viability assay, IC50=0.07181μM. SANGER
CAL-85-1 Growth inhibition assay Inhibition of human CAL-85-1 cell growth in a cell viability assay, IC50=0.07266μM. SANGER
SK-MEL-2 Growth inhibition assay Inhibition of human SK-MEL-2 cell growth in a cell viability assay, IC50=0.07316μM. SANGER
RH-18 Growth inhibition assay Inhibition of human RH-18 cell growth in a cell viability assay, IC50=0.07417μM. SANGER
EW-22 Growth inhibition assay Inhibition of human EW-22 cell growth in a cell viability assay, IC50=0.07468μM. SANGER
SK-NEP-1 Growth inhibition assay Inhibition of human SK-NEP-1 cell growth in a cell viability assay, IC50=0.07614μM. SANGER
RVH-421 Growth inhibition assay Inhibition of human RVH-421 cell growth in a cell viability assay, IC50=0.07618μM. SANGER
OMC-1 Growth inhibition assay Inhibition of human OMC-1 cell growth in a cell viability assay, IC50=0.07714μM. SANGER
LoVo Growth inhibition assay Inhibition of human LoVo cell growth in a cell viability assay, IC50=0.07856μM. SANGER
D-392MG Growth inhibition assay Inhibition of human D-392MG cell growth in a cell viability assay, IC50=0.07865μM. SANGER
HCC1187 Growth inhibition assay Inhibition of human HCC1187 cell growth in a cell viability assay, IC50=0.07933μM. SANGER
SK-MEL-28 Growth inhibition assay Inhibition of human SK-MEL-28 cell growth in a cell viability assay, IC50=0.07974μM. SANGER
KP-N-YS Growth inhibition assay Inhibition of human KP-N-YS cell growth in a cell viability assay, IC50=0.07987μM. SANGER
SK-N-FI Growth inhibition assay Inhibition of human SK-N-FI cell growth in a cell viability assay, IC50=0.08148μM. SANGER
OAW-42 Growth inhibition assay Inhibition of human OAW-42 cell growth in a cell viability assay, IC50=0.08159μM. SANGER
LS-513 Growth inhibition assay Inhibition of human LS-513 cell growth in a cell viability assay, IC50=0.08202μM. SANGER
SW1088 Growth inhibition assay Inhibition of human SW1088 cell growth in a cell viability assay, IC50=0.08214μM. SANGER
EFM-19 Growth inhibition assay Inhibition of human EFM-19 cell growth in a cell viability assay, IC50=0.08252μM. SANGER
NCI-H1651 Growth inhibition assay Inhibition of human NCI-H1651 cell growth in a cell viability assay, IC50=0.08292μM. SANGER
BPH-1 Growth inhibition assay Inhibition of human BPH-1 cell growth in a cell viability assay, IC50=0.08314μM. SANGER
MMAC-SF Growth inhibition assay Inhibition of human MMAC-SF cell growth in a cell viability assay, IC50=0.08429μM. SANGER
IA-LM Growth inhibition assay Inhibition of human IA-LM cell growth in a cell viability assay, IC50=0.08443μM. SANGER
A3-KAW Growth inhibition assay Inhibition of human A3-KAW cell growth in a cell viability assay, IC50=0.08648μM. SANGER
NCI-H1437 Growth inhibition assay Inhibition of human NCI-H1437 cell growth in a cell viability assay, IC50=0.08766μM. SANGER
LN-405 Growth inhibition assay Inhibition of human LN-405 cell growth in a cell viability assay, IC50=0.08779μM. SANGER
NCI-H446 Growth inhibition assay Inhibition of human NCI-H446 cell growth in a cell viability assay, IC50=0.09008μM. SANGER
NCI-H1092 Growth inhibition assay Inhibition of human NCI-H1092 cell growth in a cell viability assay, IC50=0.09011μM. SANGER
KYSE-150 Growth inhibition assay Inhibition of human KYSE-150 cell growth in a cell viability assay, IC50=0.09498μM. SANGER
KALS-1 Growth inhibition assay Inhibition of human KALS-1 cell growth in a cell viability assay, IC50=0.09625μM. SANGER
SJRH30 Growth inhibition assay Inhibition of human SJRH30 cell growth in a cell viability assay, IC50=0.09996μM. SANGER
LS-411N Growth inhibition assay Inhibition of human LS-411N cell growth in a cell viability assay, IC50=0.10177μM. SANGER
ESS-1 Growth inhibition assay Inhibition of human ESS-1 cell growth in a cell viability assay, IC50=0.10214μM. SANGER
C2BBe1 Growth inhibition assay Inhibition of human C2BBe1 cell growth in a cell viability assay, IC50=0.10267μM. SANGER
KYSE-520 Growth inhibition assay Inhibition of human KYSE-520 cell growth in a cell viability assay, IC50=0.10382μM. SANGER
IGROV-1 Growth inhibition assay Inhibition of human IGROV-1 cell growth in a cell viability assay, IC50=0.10398μM. SANGER
MOLT-4 Growth inhibition assay Inhibition of human MOLT-4 cell growth in a cell viability assay, IC50=0.10468μM. SANGER
MEG-01 Growth inhibition assay Inhibition of human MEG-01 cell growth in a cell viability assay, IC50=0.10505μM. SANGER
SNB75 Growth inhibition assay Inhibition of human SNB75 cell growth in a cell viability assay, IC50=0.10509μM. SANGER
SW837 Growth inhibition assay Inhibition of human SW837 cell growth in a cell viability assay, IC50=0.10658μM. SANGER
GMS-10 Growth inhibition assay Inhibition of human GMS-10 cell growth in a cell viability assay, IC50=0.10669μM. SANGER
BHY Growth inhibition assay Inhibition of human BHY cell growth in a cell viability assay, IC50=0.10706μM. SANGER
HSC-2 Growth inhibition assay Inhibition of human HSC-2 cell growth in a cell viability assay, IC50=0.1074μM. SANGER
A4-Fuk Growth inhibition assay Inhibition of human A4-Fuk cell growth in a cell viability assay, IC50=0.10761μM. SANGER
VMRC-RCZ Growth inhibition assay Inhibition of human VMRC-RCZ cell growth in a cell viability assay, IC50=0.10762μM. SANGER
SW48 Growth inhibition assay Inhibition of human SW48 cell growth in a cell viability assay, IC50=0.10778μM. SANGER
PANC-10-05 Growth inhibition assay Inhibition of human PANC-10-05 cell growth in a cell viability assay, IC50=0.10979μM. SANGER
KYSE-510 Growth inhibition assay Inhibition of human KYSE-510 cell growth in a cell viability assay, IC50=0.11035μM. SANGER
HCC2998 Growth inhibition assay Inhibition of human HCC2998 cell growth in a cell viability assay, IC50=0.11066μM. SANGER
SW962 Growth inhibition assay Inhibition of human SW962 cell growth in a cell viability assay, IC50=0.11128μM. SANGER
DU-4475 Growth inhibition assay Inhibition of human DU-4475 cell growth in a cell viability assay, IC50=0.1117μM. SANGER
CAS-1 Growth inhibition assay Inhibition of human CAS-1 cell growth in a cell viability assay, IC50=0.11615μM. SANGER
BEN Growth inhibition assay Inhibition of human BEN cell growth in a cell viability assay, IC50=0.11639μM. SANGER
TE-9 Growth inhibition assay Inhibition of human TE-9 cell growth in a cell viability assay, IC50=0.11735μM. SANGER
SCC-9 Growth inhibition assay Inhibition of human SCC-9 cell growth in a cell viability assay, IC50=0.1207μM. SANGER
LU-139 Growth inhibition assay Inhibition of human LU-139 cell growth in a cell viability assay, IC50=0.12082μM. SANGER
M14 Growth inhibition assay Inhibition of human M14 cell growth in a cell viability assay, IC50=0.12231μM. SANGER
HOP-62 Growth inhibition assay Inhibition of human HOP-62 cell growth in a cell viability assay, IC50=0.12241μM. SANGER
NCI-H720 Growth inhibition assay Inhibition of human NCI-H720 cell growth in a cell viability assay, IC50=0.12372μM. SANGER
NCI-H810 Growth inhibition assay Inhibition of human NCI-H810 cell growth in a cell viability assay, IC50=0.12501μM. SANGER
BB49-HNC Growth inhibition assay Inhibition of human BB49-HNC cell growth in a cell viability assay, IC50=0.12558μM. SANGER
A431 Growth inhibition assay Inhibition of human A431 cell growth in a cell viability assay, IC50=0.12588μM. SANGER
HAL-01 Growth inhibition assay Inhibition of human HAL-01 cell growth in a cell viability assay, IC50=0.12809μM. SANGER
NCI-H2122 Growth inhibition assay Inhibition of human NCI-H2122 cell growth in a cell viability assay, IC50=0.13028μM. SANGER
NCI-H226 Growth inhibition assay Inhibition of human NCI-H226 cell growth in a cell viability assay, IC50=0.13147μM. SANGER
NH-12 Growth inhibition assay Inhibition of human NH-12 cell growth in a cell viability assay, IC50=0.13425μM. SANGER
NCI-H520 Growth inhibition assay Inhibition of human NCI-H520 cell growth in a cell viability assay, IC50=0.13483μM. SANGER
OCI-AML2 Growth inhibition assay Inhibition of human OCI-AML2 cell growth in a cell viability assay, IC50=0.13558μM. SANGER
MDA-MB-415 Growth inhibition assay Inhibition of human MDA-MB-415 cell growth in a cell viability assay, IC50=0.13655μM. SANGER
TE-6 Growth inhibition assay Inhibition of human TE-6 cell growth in a cell viability assay, IC50=0.139μM. SANGER
SW1783 Growth inhibition assay Inhibition of human SW1783 cell growth in a cell viability assay, IC50=0.13904μM. SANGER
DB Growth inhibition assay Inhibition of human DB cell growth in a cell viability assay, IC50=0.1414μM. SANGER
NB6 Growth inhibition assay Inhibition of human NB6 cell growth in a cell viability assay, IC50=0.14232μM. SANGER
MZ1-PC Growth inhibition assay Inhibition of human MZ1-PC cell growth in a cell viability assay, IC50=0.14379μM. SANGER
KMOE-2 Growth inhibition assay Inhibition of human KMOE-2 cell growth in a cell viability assay, IC50=0.14527μM. SANGER
EFO-21 Growth inhibition assay Inhibition of human EFO-21 cell growth in a cell viability assay, IC50=0.14938μM. SANGER
HCT-15 Growth inhibition assay Inhibition of human HCT-15 cell growth in a cell viability assay, IC50=0.15005μM. SANGER
MS-1 Growth inhibition assay Inhibition of human MS-1 cell growth in a cell viability assay, IC50=0.1657μM. SANGER
AM-38 Growth inhibition assay Inhibition of human AM-38 cell growth in a cell viability assay, IC50=0.16878μM. SANGER
LOXIMVI Growth inhibition assay Inhibition of human LOXIMVI cell growth in a cell viability assay, IC50=0.17147μM. SANGER
COLO-741 Growth inhibition assay Inhibition of human COLO-741 cell growth in a cell viability assay, IC50=0.17614μM. SANGER
KINGS-1 Growth inhibition assay Inhibition of human KINGS-1 cell growth in a cell viability assay, IC50=0.17712μM. SANGER
NCI-H1623 Growth inhibition assay Inhibition of human NCI-H1623 cell growth in a cell viability assay, IC50=0.17935μM. SANGER
NCI-H1838 Growth inhibition assay Inhibition of human NCI-H1838 cell growth in a cell viability assay, IC50=0.18381μM. SANGER
COLO-680N Growth inhibition assay Inhibition of human COLO-680N cell growth in a cell viability assay, IC50=0.18702μM. SANGER
NCI-H1573 Growth inhibition assay Inhibition of human NCI-H1573 cell growth in a cell viability assay, IC50=0.1888μM. SANGER
SK-N-DZ Growth inhibition assay Inhibition of human SK-N-DZ cell growth in a cell viability assay, IC50=0.18927μM. SANGER
8305C Growth inhibition assay Inhibition of human 8305C cell growth in a cell viability assay, IC50=0.1925μM. SANGER
OCUB-M Growth inhibition assay Inhibition of human OCUB-M cell growth in a cell viability assay, IC50=0.19545μM. SANGER
LB771-HNC Growth inhibition assay Inhibition of human LB771-HNC cell growth in a cell viability assay, IC50=0.20018μM. SANGER
NCI-H1793 Growth inhibition assay Inhibition of human NCI-H1793 cell growth in a cell viability assay, IC50=0.2097μM. SANGER
HT-3 Growth inhibition assay Inhibition of human HT-3 cell growth in a cell viability assay, IC50=0.21164μM. SANGER
LCLC-97TM1 Growth inhibition assay Inhibition of human LCLC-97TM1 cell growth in a cell viability assay, IC50=0.21748μM. SANGER
TE-12 Growth inhibition assay Inhibition of human TE-12 cell growth in a cell viability assay, IC50=0.22078μM. SANGER
HCC2218 Growth inhibition assay Inhibition of human HCC2218 cell growth in a cell viability assay, IC50=0.22093μM. SANGER
GP5d Growth inhibition assay Inhibition of human GP5d cell growth in a cell viability assay, IC50=0.2262μM. SANGER
SNU-C2B Growth inhibition assay Inhibition of human SNU-C2B cell growth in a cell viability assay, IC50=0.22661μM. SANGER
U-87-MG Growth inhibition assay Inhibition of human U-87-MG cell growth in a cell viability assay, IC50=0.22753μM. SANGER
HH Growth inhibition assay Inhibition of human HH cell growth in a cell viability assay, IC50=0.22843μM. SANGER
SH-4 Growth inhibition assay Inhibition of human SH-4 cell growth in a cell viability assay, IC50=0.23264μM. SANGER
LCLC-103H Growth inhibition assay Inhibition of human LCLC-103H cell growth in a cell viability assay, IC50=0.23712μM. SANGER
KNS-42 Growth inhibition assay Inhibition of human KNS-42 cell growth in a cell viability assay, IC50=0.24283μM. SANGER
CW-2 Growth inhibition assay Inhibition of human CW-2 cell growth in a cell viability assay, IC50=0.25767μM. SANGER
NCI-N87 Growth inhibition assay Inhibition of human NCI-N87 cell growth in a cell viability assay, IC50=0.2642μM. SANGER
OAW-28 Growth inhibition assay Inhibition of human OAW-28 cell growth in a cell viability assay, IC50=0.28348μM. SANGER
NCI-H1648 Growth inhibition assay Inhibition of human NCI-H1648 cell growth in a cell viability assay, IC50=0.28554μM. SANGER
D-263MG Growth inhibition assay Inhibition of human D-263MG cell growth in a cell viability assay, IC50=0.28767μM. SANGER
RS4-11 Growth inhibition assay Inhibition of human RS4-11 cell growth in a cell viability assay, IC50=0.28947μM. SANGER
GI-ME-N Growth inhibition assay Inhibition of human GI-ME-N cell growth in a cell viability assay, IC50=0.29033μM. SANGER
JVM-3 Growth inhibition assay Inhibition of human JVM-3 cell growth in a cell viability assay, IC50=0.29281μM. SANGER
MEL-HO Growth inhibition assay Inhibition of human MEL-HO cell growth in a cell viability assay, IC50=0.30023μM. SANGER
MSTO-211H Growth inhibition assay Inhibition of human MSTO-211H cell growth in a cell viability assay, IC50=0.30254μM. SANGER
NCI-H1792 Growth inhibition assay Inhibition of human NCI-H1792 cell growth in a cell viability assay, IC50=0.30568μM. SANGER
TE-10 Growth inhibition assay Inhibition of human TE-10 cell growth in a cell viability assay, IC50=0.31694μM. SANGER
NCI-H2009 Growth inhibition assay Inhibition of human NCI-H2009 cell growth in a cell viability assay, IC50=0.31749μM. SANGER
DOHH-2 Growth inhibition assay Inhibition of human DOHH-2 cell growth in a cell viability assay, IC50=0.32805μM. SANGER
GCIY Growth inhibition assay Inhibition of human GCIY cell growth in a cell viability assay, IC50=0.32874μM. SANGER
SCH Growth inhibition assay Inhibition of human SCH cell growth in a cell viability assay, IC50=0.3391μM. SANGER
KLE Growth inhibition assay Inhibition of human KLE cell growth in a cell viability assay, IC50=0.38036μM. SANGER
BE-13 Growth inhibition assay Inhibition of human BE-13 cell growth in a cell viability assay, IC50=0.39158μM. SANGER
CAMA-1 Growth inhibition assay Inhibition of human CAMA-1 cell growth in a cell viability assay, IC50=0.39459μM. SANGER
HC-1 Growth inhibition assay Inhibition of human HC-1 cell growth in a cell viability assay, IC50=0.39991μM. SANGER
LU-134-A Growth inhibition assay Inhibition of human LU-134-A cell growth in a cell viability assay, IC50=0.40045μM. SANGER
HCC38 Growth inhibition assay Inhibition of human HCC38 cell growth in a cell viability assay, IC50=0.41829μM. SANGER
SW872 Growth inhibition assay Inhibition of human SW872 cell growth in a cell viability assay, IC50=0.44657μM. SANGER
BxPC-3 Growth inhibition assay Inhibition of human BxPC-3 cell growth in a cell viability assay, IC50=0.47501μM. SANGER
UACC-893 Growth inhibition assay Inhibition of human UACC-893 cell growth in a cell viability assay, IC50=0.48439μM. SANGER
KURAMOCHI Growth inhibition assay Inhibition of human KURAMOCHI cell growth in a cell viability assay, IC50=0.48728μM. SANGER
DU-145 Growth inhibition assay Inhibition of human DU-145 cell growth in a cell viability assay, IC50=0.50043μM. SANGER
SK-MES-1 Growth inhibition assay Inhibition of human SK-MES-1 cell growth in a cell viability assay, IC50=0.50677μM. SANGER
NKM-1 Growth inhibition assay Inhibition of human NKM-1 cell growth in a cell viability assay, IC50=0.50925μM. SANGER
TGBC11TKB Growth inhibition assay Inhibition of human TGBC11TKB cell growth in a cell viability assay, IC50=0.51476μM. SANGER
HT-1376 Growth inhibition assay Inhibition of human HT-1376 cell growth in a cell viability assay, IC50=0.53816μM. SANGER
LU-135 Growth inhibition assay Inhibition of human LU-135 cell growth in a cell viability assay, IC50=0.54563μM. SANGER
SCC-4 Growth inhibition assay Inhibition of human SCC-4 cell growth in a cell viability assay, IC50=0.54737μM. SANGER
BALL-1 Growth inhibition assay Inhibition of human BALL-1 cell growth in a cell viability assay, IC50=0.55558μM. SANGER
NCI-H1304 Growth inhibition assay Inhibition of human NCI-H1304 cell growth in a cell viability assay, IC50=0.55573μM. SANGER
CaR-1 Growth inhibition assay Inhibition of human CaR-1 cell growth in a cell viability assay, IC50=0.58618μM. SANGER
GR-ST Growth inhibition assay Inhibition of human GR-ST cell growth in a cell viability assay, IC50=0.6283μM. SANGER
COR-L88 Growth inhibition assay Inhibition of human COR-L88 cell growth in a cell viability assay, IC50=0.64357μM. SANGER
NCI-H526 Growth inhibition assay Inhibition of human NCI-H526 cell growth in a cell viability assay, IC50=0.67186μM. SANGER
MZ2-MEL Growth inhibition assay Inhibition of human MZ2-MEL cell growth in a cell viability assay, IC50=0.71038μM. SANGER
MDA-MB-175-VII Growth inhibition assay Inhibition of human MDA-MB-175-VII cell growth in a cell viability assay, IC50=0.72931μM. SANGER
KGN Growth inhibition assay Inhibition of human KGN cell growth in a cell viability assay, IC50=0.75883μM. SANGER
KARPAS-45 Growth inhibition assay Inhibition of human KARPAS-45 cell growth in a cell viability assay, IC50=0.76422μM. SANGER
SK-LMS-1 Growth inhibition assay Inhibition of human SK-LMS-1 cell growth in a cell viability assay, IC50=0.77309μM. SANGER
MFE-280 Growth inhibition assay Inhibition of human MFE-280 cell growth in a cell viability assay, IC50=0.80193μM. SANGER
ALL-PO Growth inhibition assay Inhibition of human ALL-PO cell growth in a cell viability assay, IC50=0.8079μM. SANGER
DoTc2-4510 Growth inhibition assay Inhibition of human DoTc2-4510 cell growth in a cell viability assay, IC50=0.83126μM. SANGER
SW1417 Growth inhibition assay Inhibition of human SW1417 cell growth in a cell viability assay, IC50=0.84154μM. SANGER
KE-37 Growth inhibition assay Inhibition of human KE-37 cell growth in a cell viability assay, IC50=0.87226μM. SANGER
GAK Growth inhibition assay Inhibition of human GAK cell growth in a cell viability assay, IC50=0.91357μM. SANGER
SK-MEL-1 Growth inhibition assay Inhibition of human SK-MEL-1 cell growth in a cell viability assay, IC50=0.94883μM. SANGER
HT Growth inhibition assay Inhibition of human HT cell growth in a cell viability assay, IC50=0.96058μM. SANGER
LU-99A Growth inhibition assay Inhibition of human LU-99A cell growth in a cell viability assay, IC50=0.98114μM. SANGER
EW-18 Growth inhibition assay Inhibition of human EW-18 cell growth in a cell viability assay, IC50=0.99505μM. SANGER
P30-OHK Growth inhibition assay Inhibition of human P30-OHK cell growth in a cell viability assay, IC50=1.06027μM. SANGER
CAPAN-1 Growth inhibition assay Inhibition of human CAPAN-1 cell growth in a cell viability assay, IC50=1.06876μM. SANGER
SK-MEL-24 Growth inhibition assay Inhibition of human SK-MEL-24 cell growth in a cell viability assay, IC50=1.0762μM. SANGER
ML-2 Growth inhibition assay Inhibition of human ML-2 cell growth in a cell viability assay, IC50=1.14212μM. SANGER
SK-HEP-1 Growth inhibition assay Inhibition of human SK-HEP-1 cell growth in a cell viability assay, IC50=1.15753μM. SANGER
HT55 Growth inhibition assay Inhibition of human HT55 cell growth in a cell viability assay, IC50=1.17705μM. SANGER
Calu-6 Growth inhibition assay Inhibition of human Calu-6 cell growth in a cell viability assay, IC50=1.19035μM. SANGER
Ca-Ski Growth inhibition assay Inhibition of human Ca-Ski cell growth in a cell viability assay, IC50=1.24599μM. SANGER
CAL-54 Growth inhibition assay Inhibition of human CAL-54 cell growth in a cell viability assay, IC50=1.28131μM. SANGER
HMV-II Growth inhibition assay Inhibition of human HMV-II cell growth in a cell viability assay, IC50=1.30192μM. SANGER
DMS-79 Growth inhibition assay Inhibition of human DMS-79 cell growth in a cell viability assay, IC50=1.35288μM. SANGER
NCI-H2291 Growth inhibition assay Inhibition of human NCI-H2291 cell growth in a cell viability assay, IC50=1.35312μM. SANGER
SK-MEL-3 Growth inhibition assay Inhibition of human SK-MEL-3 cell growth in a cell viability assay, IC50=1.42951μM. SANGER
COR-L23 Growth inhibition assay Inhibition of human COR-L23 cell growth in a cell viability assay, IC50=1.4298μM. SANGER
SHP-77 Growth inhibition assay Inhibition of human SHP-77 cell growth in a cell viability assay, IC50=1.45832μM. SANGER
KM12 Growth inhibition assay Inhibition of human KM12 cell growth in a cell viability assay, IC50=1.47664μM. SANGER
K-562 Growth inhibition assay Inhibition of human K-562 cell growth in a cell viability assay, IC50=1.47985μM. SANGER
SW1463 Growth inhibition assay Inhibition of human SW1463 cell growth in a cell viability assay, IC50=1.56644μM. SANGER
MC116 Growth inhibition assay Inhibition of human MC116 cell growth in a cell viability assay, IC50=1.59879μM. SANGER
no-10 Growth inhibition assay Inhibition of human no-10 cell growth in a cell viability assay, IC50=1.60982μM. SANGER
T84 Growth inhibition assay Inhibition of human T84 cell growth in a cell viability assay, IC50=1.7516μM. SANGER
IGR-1 Growth inhibition assay Inhibition of human IGR-1 cell growth in a cell viability assay, IC50=1.75671μM. SANGER
U-118-MG Growth inhibition assay Inhibition of human U-118-MG cell growth in a cell viability assay, IC50=1.88558μM. SANGER
NCI-H2087 Growth inhibition assay Inhibition of human NCI-H2087 cell growth in a cell viability assay, IC50=1.89044μM. SANGER
D-542MG Growth inhibition assay Inhibition of human D-542MG cell growth in a cell viability assay, IC50=1.90441μM. SANGER
NCI-H727 Growth inhibition assay Inhibition of human NCI-H727 cell growth in a cell viability assay, IC50=1.94908μM. SANGER
SW684 Growth inhibition assay Inhibition of human SW684 cell growth in a cell viability assay, IC50=2.03866μM. SANGER
Capan-2 Growth inhibition assay Inhibition of human Capan-2 cell growth in a cell viability assay, IC50=2.04183μM. SANGER
HT-29 Growth inhibition assay Inhibition of human HT-29 cell growth in a cell viability assay, IC50=2.04276μM. SANGER
KASUMI-1 Growth inhibition assay Inhibition of human KASUMI-1 cell growth in a cell viability assay, IC50=2.09155μM. SANGER
ATN-1 Growth inhibition assay Inhibition of human ATN-1 cell growth in a cell viability assay, IC50=2.0956μM. SANGER
JVM-2 Growth inhibition assay Inhibition of human JVM-2 cell growth in a cell viability assay, IC50=2.14047μM. SANGER
SK-MEL-30 Growth inhibition assay Inhibition of human SK-MEL-30 cell growth in a cell viability assay, IC50=2.38457μM. SANGER
COLO-668 Growth inhibition assay Inhibition of human COLO-668 cell growth in a cell viability assay, IC50=2.50458μM. SANGER
EM-2 Growth inhibition assay Inhibition of human EM-2 cell growth in a cell viability assay, IC50=2.51815μM. SANGER
UMC-11 Growth inhibition assay Inhibition of human UMC-11 cell growth in a cell viability assay, IC50=2.60698μM. SANGER
MG-63 Growth inhibition assay Inhibition of human MG-63 cell growth in a cell viability assay, IC50=2.8112μM. SANGER
NCI-SNU-5 Growth inhibition assay Inhibition of human NCI-SNU-5 cell growth in a cell viability assay, IC50=2.863μM. SANGER
NOMO-1 Growth inhibition assay Inhibition of human NOMO-1 cell growth in a cell viability assay, IC50=2.90568μM. SANGER
NCI-H209 Growth inhibition assay Inhibition of human NCI-H209 cell growth in a cell viability assay, IC50=3.00673μM. SANGER
CTV-1 Growth inhibition assay Inhibition of human CTV-1 cell growth in a cell viability assay, IC50=3.01648μM. SANGER
NCI-H1770 Growth inhibition assay Inhibition of human NCI-H1770 cell growth in a cell viability assay, IC50=3.02207μM. SANGER
RCM-1 Growth inhibition assay Inhibition of human RCM-1 cell growth in a cell viability assay, IC50=3.03156μM. SANGER
Calu-3 Growth inhibition assay Inhibition of human Calu-3 cell growth in a cell viability assay, IC50=3.16226μM. SANGER
NCI-H630 Growth inhibition assay Inhibition of human NCI-H630 cell growth in a cell viability assay, IC50=3.43203μM. SANGER
SW1116 Growth inhibition assay Inhibition of human SW1116 cell growth in a cell viability assay, IC50=3.62799μM. SANGER
RMG-I Growth inhibition assay Inhibition of human RMG-I cell growth in a cell viability assay, IC50=3.84056μM. SANGER
RCC10RGB Growth inhibition assay Inhibition of human RCC10RGB cell growth in a cell viability assay, IC50=4.53554μM. SANGER
C3A Growth inhibition assay Inhibition of human C3A cell growth in a cell viability assay, IC50=4.63097μM. SANGER
C8166 Growth inhibition assay Inhibition of human C8166 cell growth in a cell viability assay, IC50=4.94603μM. SANGER
MOLT-13 Growth inhibition assay Inhibition of human MOLT-13 cell growth in a cell viability assay, IC50=5.5543μM. SANGER
NCI-H2029 Growth inhibition assay Inhibition of human NCI-H2029 cell growth in a cell viability assay, IC50=5.59003μM. SANGER
HDLM-2 Growth inhibition assay Inhibition of human HDLM-2 cell growth in a cell viability assay, IC50=5.67384μM. SANGER
ACHN Growth inhibition assay Inhibition of human ACHN cell growth in a cell viability assay, IC50=5.71551μM. SANGER
NCI-H69 Growth inhibition assay Inhibition of human NCI-H69 cell growth in a cell viability assay, IC50=5.96973μM. SANGER
ECC10 Growth inhibition assay Inhibition of human ECC10 cell growth in a cell viability assay, IC50=6.27244μM. SANGER
CFPAC-1 Growth inhibition assay Inhibition of human CFPAC-1 cell growth in a cell viability assay, IC50=6.38606μM. SANGER
KU812 Growth inhibition assay Inhibition of human KU812 cell growth in a cell viability assay, IC50=7.31846μM. SANGER
L-428 Growth inhibition assay Inhibition of human L-428 cell growth in a cell viability assay, IC50=7.64645μM. SANGER
LU-65 Growth inhibition assay Inhibition of human LU-65 cell growth in a cell viability assay, IC50=7.66066μM. SANGER
KY821 Growth inhibition assay Inhibition of human KY821 cell growth in a cell viability assay, IC50=9.74408μM. SANGER
HCC1569 Growth inhibition assay Inhibition of human HCC1569 cell growth in a cell viability assay, IC50=10.3717μM. SANGER
OE33 Growth inhibition assay Inhibition of human OE33 cell growth in a cell viability assay, IC50=11.9163μM. SANGER
NCI-H460 Growth inhibition assay Inhibition of human NCI-H460 cell growth in a cell viability assay, IC50=11.9629μM. SANGER
CCRF-CEM Growth inhibition assay Inhibition of human CCRF-CEM cell growth in a cell viability assay, IC50=12.0256μM. SANGER
MFH-ino Growth inhibition assay Inhibition of human MFH-ino cell growth in a cell viability assay, IC50=12.2311μM. SANGER
HCC1954 Growth inhibition assay Inhibition of human HCC1954 cell growth in a cell viability assay, IC50=12.6636μM. SANGER
SW948 Growth inhibition assay Inhibition of human SW948 cell growth in a cell viability assay, IC50=14.1953μM. SANGER
NCI-H82 Growth inhibition assay Inhibition of human NCI-H82 cell growth in a cell viability assay, IC50=14.6264μM. SANGER
KM-H2 Growth inhibition assay Inhibition of human KM-H2 cell growth in a cell viability assay, IC50=15.7903μM. SANGER
OE19 Growth inhibition assay Inhibition of human OE19 cell growth in a cell viability assay, IC50=16.5176μM. SANGER
COLO-320-HSR Growth inhibition assay Inhibition of human COLO-320-HSR cell growth in a cell viability assay, IC50=16.92μM. SANGER
NCI-H441 Growth inhibition assay Inhibition of human NCI-H441 cell growth in a cell viability assay, IC50=20.1493μM. SANGER
A388 Growth inhibition assay Inhibition of human A388 cell growth in a cell viability assay, IC50=21.4044μM. SANGER
NCI-H1993 Growth inhibition assay Inhibition of human NCI-H1993 cell growth in a cell viability assay, IC50=22.4278μM. SANGER
LS-1034 Growth inhibition assay Inhibition of human LS-1034 cell growth in a cell viability assay, IC50=23.2936μM. SANGER
NCI-H1666 Growth inhibition assay Inhibition of human NCI-H1666 cell growth in a cell viability assay, IC50=33.2038μM. SANGER
NCI-H1975 Growth inhibition assay Inhibition of human NCI-H1975 cell growth in a cell viability assay, IC50=35.902μM. SANGER
클릭하여 더 많은 세포주 실험 데이터 보기

화학 정보, 보관 및 안정성 (Chemical Information, Storage & Stability)

분자량 400.5 화학식

C19H20N4O2S2

 보관 (수령일로부터)
CAS 번호 488832-69-5 SDF 다운로드 원액 보관

동의어 N/A Smiles CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2

용해도 (Solubility)

In vitro
배치:

DMSO : 80 mg/mL (199.75 mM)
(수분으로 오염된 DMSO는 용해도를 감소시킬 수 있습니다. 신선하고 무수 DMSO를 사용하십시오.)

Water : Insoluble

Ethanol : Insoluble

몰농도 계산기

질량 농도 부피 분자량
희석 계산기 분자량 계산기

In vivo
배치:

생체 내 제형 계산기 (투명한 용액)

1단계: 아래 정보 입력 (권장: 실험 중 손실을 고려하여 추가 동물 포함)

mg/kg g μL

2단계: 생체 내 제형 입력 (이것은 계산기일 뿐 제형이 아닙니다. 용해도 섹션에 생체 내 제형이 없는 경우 먼저 당사에 문의하십시오.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

계산 결과:

작업 농도: mg/ml;

DMSO 원액 준비 방법: mg 약물 사전 용해 μL DMSO ( 원액 농도 mg/mL, 농도가 해당 약물 배치의 DMSO 용해도를 초과하는 경우 먼저 당사에 문의하십시오. )

생체 내 제형 준비 방법: 취하다 μL DMSO 원액, 다음 추가μL PEG300, 혼합하고 투명하게 한 다음 추가μL Tween 80, 혼합하고 투명하게 한 다음 추가 μL ddH2O, 혼합하고 투명하게 합니다.

생체 내 제형 준비 방법: 취하다 μL DMSO 원액, 다음 추가 μL 옥수수 기름, 혼합하고 투명하게 합니다.

참고: 1. 다음 용매를 추가하기 전에 액체가 투명한지 확인하십시오.
2. 용매를 순서대로 추가해야 합니다. 다음 용매를 추가하기 전에 이전 추가에서 얻은 용액이 투명한 용액인지 확인해야 합니다. 와동, 초음파 또는 뜨거운 물 중탕과 같은 물리적 방법을 사용하여 용해를 도울 수 있습니다.

작용 메커니즘 (Mechanism of Action)

Targets/IC50/Ki
HSP70
(Cell-free assay)
시험관 내(In vitro)

Elesclomol (STA-4783) significantly induces the expression of heat shock stress response genes and metallothionein genes, a signature transcription profile indicative of oxidative stress in Hs294T cells. This compound (100 nM) rapidly induces Hsp70 RNA levels with a 4.8-fold increase at 1 hour and a 160-fold increase at 6 hours in Ramos Burkitt's lymphoma B cells in consistent with the intracellular ROS content which increases by 20% as early as 0.5 hour and 385% at 6 hours, and the induction of Hsp70 can be blocked by antioxidants NAC and Tiron pretreatment. It increases the number of early and late apoptotic cells with 3.7- and 11-fold through the induction of oxidative stress, which can be completely blocked by NAC, while having little effect on normal cells. The agent significantly inhibits the cell viability of SK-MEL-5, MCF-7, and HL-60 with IC50 of 110 nM, 24 nM and 9 nM, respectively. This chemical induces copper-dependent ROS generation and cytoxicity in yeast. Instead of working through a specific cellular protein target, it interacts with the electron transport chain (ETC), a biologically coherent set of processes occurring in the mitochondrion, to generate high levels of ROS within the organelle and consequently cell death.

생체 내(In vivo)

Although Elesclomol (STA-4783) (25-100 mg/kg) as a single agent shows no antitumor activity in nude mouse xenograft models of human breast cancers (MDA435, MCF7 and ZR-75-1), lung cancer (RER) or lymphoma (U937), this compound substantially enhances the efficacy of chemotherapeutic agents in these models, both in terms of tumor regression and extended survival of mice.

참조
  • [4] https://pubmed.ncbi.nlm.nih.gov/16784029/
  • [5] https://pubmed.ncbi.nlm.nih.gov/35298263/

임상시험 정보 (Clinical Trial Information)

(데이터 출처 https://clinicaltrials.gov, 업데이트 날짜 2024-05-22)

NCT 번호 모집 조건 스폰서/협력자 시작일 단계
NCT00827203 Suspended
Metastatic Solid Tumors
Synta Pharmaceuticals Corp.
 January 2009 Phase 1
NCT00808418 Completed
Prostate Cancer
Synta Pharmaceuticals Corp.
 November 2008 Phase 1

자주 묻는 질문 (Frequently Asked Questions)

질문 1:
How can we use it for in vivo mouse studies?

답변:
It is fine for oral administration as a suspension in 1% DMSO+30% polyethylene glycol+1% Tween 80. You can also dissolve this compound in 0.5-1% CMC-Na solution and treat the mice by oral gavage.